(Feel free to update this bug's summary to be more specific.)
Component Readiness has found a potential regression in the following test:

install should succeed: overall

Extreme regression detected.
Fishers Exact probability of a regression: 100.00%.
Test pass rate dropped from 99.05% to 68.94%.
Overrode base stats using release 4.17

Sample (being evaluated) Release: 4.19
Start Time: 2025-04-16T00:00:00Z
End Time: 2025-04-23T23:59:59Z
Success Rate: 68.94%
Successes: 91
Failures: 41
Flakes: 0

Base (historical) Release: 4.17
Start Time: 2024-09-01T00:00:00Z
End Time: 2024-10-01T00:00:00Z
Success Rate: 99.05%
Successes: 940
Failures: 9
Flakes: 0

View the test details report for additional context.

Found NAT quota issue in the following job:
https://prow.ci.openshift.org/view/gs/test-platform-results/logs/periodic-ci-openshift-release-master-nightly-4.19-e2e-aws-driver-toolkit/1914285432418340864

time="2025-04-21T12:09:48Z" level=debug msg="I0421 12:09:48.829279     582 recorder.go:104] \"Failed to create new NAT Gateway: RequestLimitExceeded: Request limit exceeded.\\n\\tstatus code: 503, request id: 4fa8cfc6-9dd2-4129-b43a-6bc9b8d0f623\" logger=\"events\" type=\"Warning\" object={\"kind\":\"AWSCluster\",\"namespace\":\"openshift-cluster-api-guests\",\"name\":\"ci-op-hjs2wfwl-f6eaa-xpd7c\",\"uid\":\"9a5bb7be-610e-4a2c-9e99-be489921245c\",\"apiVersion\":\"infrastructure.cluster.x-k8s.io/v1beta2\",\"resourceVersion\":\"353\"} reason=\"FailedCreateNATGateway\""