Hibernate 3.3 (and later) uses a different mechanism to configure the 2nd level cache, using the hibernate.cache.region.factory_class instead of the hibernate.cache.provider_class that was used prior to Hibernate 3.3. For example, see the Ehcache documentation and the Infinispan documentation.

Also, the Infinispan 2nd level cache has an additional optional property when looking in JNDI for the cache manager.