If the corresponding binding service (the service responsible for creating the jndi binding) is not ACTIVE (e.g. clustering binding services are always PASSIVE) or, due to a race condition, has not yet started completely, a null value will be returned.
The ee subsystem processes @Resource(lookup=...) correctly by establishing a dependency on the corresponding binder service.

This is newly problematic for EAP 7.4, where the Infinispan APIs are public.
Thus, users attempting to inject, for example, a server managed cache into a CDI bean will fail during runtime.
e.g.

@Resource(lookup="java:jboss/infinispan/cache/foo/bar")
private Cache<?, ?> cache;