I would like to activate a set of beans at application start-time. Currently I can use Programmatic lookup in CDI for dynamically injecting the beans. But I believe it'll be easier with better support for this.

Spring has a nice support for this with the concept of a 'Profile':
https://spring.io/blog/2011/02/14/spring-3-1-m1-introducing-profile/

Would be really helpful if CDI has support for this.